Provides a grounding in molecular biology and a working knowledge of recombinant DNA technology, thus establishing a basis for the evaluation and application of genetic engineering in whole animal systems. Beginning with the basic principles of genetics, this course examines the use of molecular methods to study gene expression, deliver viral and non-viral vectors, and its critical role in health. Prerequisite: BME 2101. Co-requisites: BME 2104.

Introduces principles of continuum mechanics of biological tissues & systems. 1) Review results used in biomechanics field, 2) properties of living tissue; 3) mechanical basis & effects of pathology & trauma: 4) intro to mechanotransduction, circulatory transport, growth & remodeling & tissue-engineered materials; 5) low Reynolds number flows in vivo & microsystems. Prerequisites: APMA 2120 or MATH 2310 or MATH 2315 and BME Major or Minor

You will learn how excitable tissue, nerves and muscle, and the cardiovascular and respiratory systems function. You will develop an understanding of mechanisms, with an introduction to structure, an emphasis on quantitative analysis, and integration of hormonal and neural regulation and control. Prerequisites: (PHYS 1425 or PHYS 1420 or PHYS 1710) AND (APMA 1110 or MATH 1320) AND (CHEM 1410 or CHEM 1610 or CHEM 1810) AND BME Major or Minor

Intro to fundamentals of cell structure and function, emphasizing the techniques and technologies available for the study of cell biology. Content includes cell structure and function; energy flow in cells; information flow in cells focuses on modern molecular biology and genetic engineering, and includes DNA replication, the cell cycle, gene expression, gene regulation, and protein synthesis. Prerequisite: CHEM 1410 or CHEM 1610 or CHEM 1810 or instructor permission.

Introduces principles and application of fluid and mass transport processes in cell, tissue and organ systems. Topics include intro to physiological fluid mechanics in the circulation and tissue, fundamentals of mass transport in biological systems, effects of mass transport and biochemical interactions at the cell and tissue scales and fluid and mass transport in organs. Prerequisites: APMA 2130 or MATH 3250, or APMA 2501 - Differential Equations & Linear Algebra, and BME 2101, and BME 2104, or instructor permission.

Presents analytical tools used to model signals & linear systems. BME examples include multicompartment modeling of drug delivery, modeling of dynamic biomechanical systems & electrical circuit models of excitable cells. Topics: signals & systems, convolution, continuous time Fourier transforms, electrical circuits & applications of linear system theory. Prerequisite: PHYS 2415 & APMA 2130, & CS 1110 or equivalent

Introduces the physiology of the kidney, salt and water balance, gastrointestinal system, endocrine system, and central nervous system, with reference to diseases and their pathophysiology. Prerequisite: (CHEM 1410 or CHEM 1610 or CHEM 1810) AND (PHYS 1425 or PHYS 1420 or PHYS 1710) AND BME 2101, or instructor permission.

A year-long course integrating concepts and skills from prior courses to formulate and solve problems in biomedical systems, including experimental design, performance and analysis. Testing in tissues/cells & manipulation of molecular constituents to determine structural and functional characteristics for design of therapeutic or measurement systems. Methods incl biochemical, physiological, cell biology, mechanical, electrical and computer, systems, chemical, imaging, and other approaches. Prerequisite: 3rd and 4th Year standing in Biomedical Engineering major

Introduces techniques for constructing predictive or analytical engineering models for biological processes. Teaches modeling approaches using example problems in transport, mechanics, bioelectricity, molecular dynamics, tissue assembly & imaging. Problem sets include 1) linear systems and filtering 2) compartmental modeling 3) numerical techniques 4) finite element / finite difference models and 5) computational automata models. Prereq: CS 1110 or CS 1111 or CS 1112. Co-requisites: APMA 2130 or MATH 3250 or APMA 2501- Differential Equations & Linear Algebra or instructor permission.

Introduces biomaterials science and biological interactions with materials with overview of biomaterials testing (in vitro and in vivo) and characterization. Emphasis on emerging novel strategies and design of biomaterials. Areas of concentration include polymers and ceramics in biomaterials, drug delivery, tissue engineering (orthopaedic and vascular) and nanotechnology. Prerequisite: BME 2101, BME 2104, or instructor permission.