Avoid at all costs. He is just awful.

Grisham is very enthusiastic about this subject but the class requires tons of memorization. That would be fine except for the fact that he expects you memorize a lot of random facts that seem irrelevant. The exam material largely corresponds to the lecture material. The project that takes place for the final exam is very poorly run by the TA and is annoying.

Grisham definitely knows his stuff, but the pure amount of info in this class makes it tough. Study hard and good grades are definitely possible.

This class was very challenging because of the shear amount of information you had to memorize. Overall, the material is very interesting and Grisham really does know his stuff. However, the test are very hard with low averages.

This class is absurdly difficult, but the curve is great.

This class is probably going to be one of the hardest that you take at UVA. Be ready to do a lot of work, especially reading the textbook, doing the end-of-chapter problems, and memorizing random facts. Attend the class because he emphasizes certain concepts/problems and stay on top of the reading. Also, if they continue the protein molecular document project, do not wait till the last minute because it is too much work and the T.A's are very helpful in advance. Overall the material is very interesting if you want to learn about the field or sciences in general.

This class sucks but a lot of it is knowing what kind of questions he's going to ask on the test...seems like structure drawing and mechanisms were emphasized much more than knowing concepts

Very difficult course, average on the first exam was a 37%. Grisham wrote the textbook, which is actually pretty decent (for a book about bio molecules of course), but because of that expects you to know pretty much EVERYTHING covered in it, which is pretty much impossible. The course therefore requires a ton of studying to do well, a TON. 3 midterms $25%, and just began a "molecular document" project, which involves writing reports and modeling a presentation on a protein.

The modeling project was also fairly horrible, he gets all excited by how cool it is for all of us to makes a presentation on a protein with 3-D modeling, but the reality is that the program is very buggy, unintuitive, and takes forever to learn. It requires another big time commitment on top of the rest of course. And because the whole course is just on a curve, it won't help your grade.

great professor. enthusiastic about his subject and extremely knowledgeable. the class is hard, he clarifies that at the beginning. he wrote the textbook so expect to learn everything for the test.

Definitely worthwhile if you come prepared to work. If you don't have at least 10 hours a week to dedicate to studying, it is extremely difficult to do well. A lot of memorization and application is involved.